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Pathological Gambling after Bilateral Subthalamic Nucleus Stimulation in Parkinson Disease
JNNP 78:517-519, Smeding,H.M.M.,et al, 2007
See this aricle in Pubmed

Article Abstract
We describe a patient with advanced Parkinsons disease who developed pathological gambling within a month after successful bilateral subthalamic nucleus (STN) stimulation. There was no history of gambling. On neuropsychological testing, slight cognitive decline was evident 1 year after surgery. Stimulation of the most dorsal contact with and without medication induced worse performances on decision making tests compared with the more ventral contact. Pathological gambling disappeared after discontinuation of pergolide and changing the stimulation parameters. Pathological gambling does not seem to be associated with decision making but appears to be related to a combination of bilateral STN stimulation and treatment with dopamine agonists.
 
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complications
iatrogenic neurologic disorders
neurologic complications of,surgery
Parkinson disease
Parkinson disease,surgical treatment of
pathologic gambling
stimulation,deep brain
stimulation,deep brain,bilateral

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